bulbine natalensis human studies

The optimal dosage for testosterone effects was found to be 50 mg/kg in rat studies. It’s easy to see why – the effects of extracts of Bulbine natalensis recorded in animal studies are amazing. ProLensis™ is a well-studied specific extract of bulbine natalensis, with several animal model studies demonstrating the benefit for controlling the hormones testosterone and estrogen – both hormones involved in body augmentation. Human studies are needed, however. There are few herbs that actually boost testosterone, fewer that really lower estrogen, but none that do both exceptionally well – except Bulbine Natalensis.. Bulbine natalensis is a plant indigenous to Africa, traditionally used as an aphrodisiac and tonic in tribesmen. Editor’s Note: While the potential increase in DHT does not concern me, as noted several times throughout other articles on iTestosterone; I prefer to focus heavily on supplements proven in human based case studies. Bulbine Natalensis Recommended Dosage, Benefits, and Side Effects. Let’s take a look at what science is saying about this compound, the benefits of it, and whether you should use it to boost testosterone and sex drive. Bulbine Natalensis is a natural herb that originates from the South and South Eastern parts of Africa. The aqueous extract of Bulbine natalensis stem at these doses (25 and 50 mg/kg body weight) may be used in the management of disorders of desire/libido, premature ejaculation and erectile dysfunction in males. Stefan Gafner, PhD, ABC’s chief science officer, said: “We are grateful to Afrigetics Botanicals for its adoption of Bulbine natalensis. Today, it is touted as a potent testosterone booster.. Bulbine natalensis has been shown to increase testosterone levels in rats, but there is currently no research demonstrating this effect in humans. In the wellness group, clients regularly devour Bulbine Natalensis with the objective of expanding testosterone and sex drive. A dosage of 50 mg/kg was established as optimal in rat studies. ), Bulbine Natalensis clocks in at 247% (i.e. When he’s not in the gym or on the road, he enjoys reading and salsa dancing. Bulbine natalensis is a plant indigenous to Africa, traditionally used as an aphrodisiac and tonic in tribesmen. Rat studies investigating how bulbine natalensis interacts with testosterone note that 50mg/kg (of a 10:1 extraction) appear to be the optimal dosage, and based on Body Surface Area Conversions, this correlates into an estimated human dose of 8mg/kg or:. It has also been shown to exhibit potent aphrodisiac qualities. In two animal-based studies, Bulbine Natalensis was shown to significantly increase testosterone levels. While I agree with the overall assessment in this article, as I always say, what works in rats usually does not end up working in humans. Questions about your PRWeb account or interested in learning more about our news services? 730mg for a 200lb person. Bulbine natalensis is quickly gaining popularity in the sports supplement world. Frost tender evergreen perennial, broad sharp pointed fleshy yellow-green leaves. These findings have since been reproduced in unpublished human studies, and today ProLensis™ features in some of the most popular testosterone-boosting dietary supplements available. These doses are currently only estimates, but … The Dangers of Bulbine Natalensis. Looking through user reviews, you’ll find that the only common negative complaint is that certain brands didn’t work; there are no reports of any horror-story side effects. For more information about ProLensis™ or to order ProLensis™ for your own product line please visit http://www.ProLensis.com or contact info(at)ProLensis(dot)com. David Sautter is a NASM-certified personal trainer, NASM-certified fitness nutrition specialist, ACE-certified sports conditioning specialist, and health and fitness writer featured in Cellucor and Workout Labs. At the conclusion of the trial, ProLensis™ was found to be as safe as a maltodextrin placebo. The gel from the leaves of Bulbine natalensis (BN) and Bulbine frutescens (BF) is commonly used as a traditional medicine in South Africa for the treatment of skin wounds and burns. What’s more, as mentioned above, one study confirmed the safety of it for the same period of a supplement cycle: four weeks. After 30, a man can expect to lose 1% of his testosterone a year, year on year. Another study mirrored these benefits, confirming the superiority of the 25 mg to 50 mg per kilogram of bodyweight dosage. Bulbine Natalensis and the Importance of Natural Testosterone Production. Aqueous extract of Bulbine natalensis Baker (Asphodelaceae) stem at 25, 50 and 100 mg/kg body weight was investigated for anabolic and androgenic effects in male Wistar rats. Group A (control) was orally treated with 0.5 mL of disti … With that said, the effect from Bulbine Natalensis was so dramatic that researchers concluded Bulbine Natalensis may promote liver side effects that are comparable to a steroid cycle. Journal of the International Society of Sports Nutrition (JISSN). Studies have shown that it increases circulating testosterone significantly with dosage of 50 mg/kg bodyweight. Its long-term effects are unknown, but a clinical study of its use in men for a period of 28 days stated that the supplement is safe according to various markers of health, including blood, kidney, liver and heart markers. Despite the herb’s documented benefits and uses in traditional medicine, current studies on B. natalensis are scant. In 2009 researchers at the University of Ford Hare in South Africa published the results of an animal study in which they had given male rats water-based extracts of Bulbine natalensis for a week. The rodent data suggests a testosterone boost of 347% compared to baseline, while lowering estrogen by 35%. Native to South Africa, Bulbine Natalensis has long been used in traditional medicine as a way to improve libido and sexual performance in men. There is evidence from the limited studies undertaken on Bulbine Natalensis to suggest that there is a toxic effect, specifically relating to the liver. 1.0) 4 weeks ago I have been fixing and dealing with the issues and constructive criticism the project received on the first post. Bulbine natalensis is a medicinal herb, selling as natural testosterone booster and widely used for enhancing the male sexual performance.. B. natalensis extracts and its constituents activated PXR and induced mRNA expression of cytochrome P450 genes resulting into an increased activity of CYP3A4 and CYP2C9 enzymes in hepatic cells.. Potential Organ Risk: One study involving rats found that although Bulbine Natalensis did boost testosterone and libido, it also shrunk the liver and kidneys. The very word testosterone produces an image of an “Alpha male” Blood, sweat and cold iron. Treatment with both leaf gel extracts has previously been demonstrated to increase tensile strength and protein and DNA content in pig dermal wounds. you will end up with a total of 347% of your original level). Check out our article on the 7 best natural testosterone boosters. It’s essential to note that except for one all studies analyzing the impacts of Bulbine Natalensis have been performed on rats instead of people. ©Copyright 1997-2015, Vocus PRW Holdings, LLC. As yet, the limited number of human studies undertaken have either failed to reproduce these results or shown no impact on testosterone levels at all. 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